When to Start Deworming Your Puppy: Everything You Need to Know

Introduction
Parasite control is a cornerstone of puppy health, with many infections acquired prior to birth or during nursing. Determining the correct time to initiate deworming safeguards puppies from early health complications. This guide provides evidence-based recommendations on when and how to start deworming your puppy.

1. Ideal Age to Begin Deworming

Two Weeks of Age
- Reason: Puppies can contract roundworms from their mother in utero and through milk.
- Initial Medication: Pyrantel pamoate, 5 mg/kg, orally; repeat every 2 weeks until 12 weeks.
Four to Six Weeks of Age
- Medication Addition: Introduce fenbendazole (50 mg/kg once daily for 3 consecutive days) if mixed infections are suspected.
- Fecal Exam: Perform a fecal float to identify specific parasite burdens and adjust treatment accordingly.

2. Standard Deworming Protocol

Age	Medication	Dosage	Notes
2 Weeks	Pyrantel Pamoate	5 mg/kg orally	First dose; covers roundworms, hookworms
4 Weeks	Pyrantel Pamoate	5 mg/kg orally	Second dose; add fenbendazole if needed
6 Weeks	Fenbendazole	50 mg/kg once daily for 3 days	Targets broad-spectrum parasites
8 Weeks	Pyrantel Pamoate	5 mg/kg orally	Third dose
10 Weeks	Fenbendazole	50 mg/kg once daily for 3 days	Continued broad coverage
12 Weeks	Pyrantel Pamoate/Praziquantel	5 mg/kg pyrantel, 5–10 mg/kg praziquantel	Comprehensive tapeworm coverage

3. Role of Veterinary Examination

Initial Check-Up (6–8 Weeks):
- Physical exam, weight measurement, and baseline fecal test.
- Tailor deworming protocol based on parasite load and overall health.
Follow-Up Visits:
- Every 2–4 weeks until 12 weeks to reassess parasite status.
- After 12 weeks, transition to a maintenance schedule (every 3–6 months).

4. Monitoring and Hygiene Measures

Stool Monitoring: Inspect daily for evidence of worms, diarrhea, or blood.
Clean Environment:
- Disinfect bedding and living areas weekly.
- Remove feces promptly to interrupt parasite life cycles.
Nutrition and Immune Support:
- Provide high-quality puppy food to boost immunity.
- Consider probiotics after deworming to restore gut flora.

5. Special Considerations

Breed Susceptibility: Certain breeds (e.g., Greyhounds) may require dose adjustments due to lean body mass.
Concurrent Vaccinations: Schedule vaccinations after completing initial deworming to ensure the puppy’s immune system responds effectively.
Signs of Adverse Reactions: Monitor for vomiting, diarrhea, or lethargy post-medication; contact veterinarian if severe.

Conclusion
Initiating deworming at two weeks of age and following a structured, veterinarian-guided schedule protects puppies from the earliest parasite threats. Combined with regular fecal exams, sanitation, and proper nutrition, this approach ensures optimal health and development.